Metastatic endometrial stromal sarcoma in a patient with refractory abnormal uterine bleeding: case report
DOI:
https://doi.org/10.5327/JBG-2965-3711-2024134101Keywords:
endometrial neoplasms, endometrial stromal sarcoma, immunohistochemistryAbstract
Introduction: Endometrial stromal sarcomas are rare, originating in the supportive tissue of endometrial glands. They are classified into low-grade (LG-ESS), high-grade, and undifferentiated. LG-ESS, known for their aggressiveness, typically present symptoms such as abnormal uterine bleeding, pelvic pain, and dysmenorrhea. Case report: A 44-year-old woman initially diagnosed with epithelioid leiomyoma. Two years later, the fibroid delivered, suggesting LG-ESS upon histopathological evaluation. Total hysterectomy confirmed the diagnosis through immunohistochemistry. Metastases to the liver, lungs, ovaries, lymph nodes, and peritoneal cavity ensued, leading to the patient's demise. Conclusion: The diagnosis is challenging, often mistaken for other tumors. Extra-genital metastases may arise years after the initial diagnosis, requiring continuous monitoring.
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